| Definition: An interaction in which at least one participant is a physical entity, e.g. a binding event.
Comment: This class should be used by default for representing molecular interactions, such as those defined by PSI-MI level 2. The participants in a molecular interaction should be listed in the PARTICIPANTS slot. Note that this is one of the few cases in which the PARTICPANT slot should be directly populated with instances (see above comments on the PARTICPANTS in the interaction class description). If sufficient information on the nature of a molecular interaction is available, a more specific BioPAX interaction class may be used. It is expected that a geneticInteraction class will be added as a sibling to physicalInteraction in a future level, hence the specialization of the interaction class to physicalInteraction.
Example: Two proteins observed to interact in a yeast-two-hybrid experiment. |